Megaloblastic Anaemia Associated with Adult Scurvy

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Megaloblastic anaemia associated with adult scurvy.

Nowadays scurvy is fortunately rare. Cases are still found among the inmates of common lodging houses and those living alone, where age, decrepitude, or apathy may have led to an inadequate dietary intake. Rigid dieting as in peptic ulcer' may be an unusual cause. While the blood picture may show little change in the milder cases, anaemia of variable degree occurs in most adults with scurvy. It...

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Megaloblastic anaemia associated with anticonvulsant therapy.

In 1954 Badenoch described two cases of megaloblastic anaemia which developed in epileptics while under treatment with phenytoin sodium and phenobarbitone, and subsequently I2 further cases have been recorded (Hawkins and Meynell, 1954; Chalmers and Boheimer, I954; Rhind and Varadi, I954; Webster, 1954; Berlyne, Levene and McGlashan, 1955; Ryan and Forshaw, I955; Vaishnava, I955). Six of these ...

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Rare case with megaloblastic anaemia.

A nine years old boy presented with history of pallor and anaemia since early infancy along with neural hearing loss responding to empirical multivitamin and folic acid therapy started on basis of blood complete picture showing anaemia and megaloblastic anaemia. On investigation he was diagnosed with Thiamine Responsive Megaloblastic Anaemia, a very rare condition in our settings.

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Pigmentation in megaloblastic anaemia associated with pregnancy and lactation.

Generalized skin pigmentation in five African women with megaloblastic anaemia in the postnatal period was associated with low serum folate levels, as distinct from vitamin B(12) deficiency. It is suggested that the occurrence of pigmentation in both folate and vitamin B(12) deficiency may reflect a common abnormality of metabolism.

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Aminoaciduria and megaloblastic anaemia.

Urinary amino-acid chromatograms from 23 patients with megaloblastic anaemia have been studied before and after therapy. The most consistent abnormality was an increased taurine or increased taurine/glycine ratio. This was not related directly to deficiency of vitamin B(12) or folic acid or to the degree of anaemia.

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1960

ISSN: 0032-5473

DOI: 10.1136/pgmj.36.418.502